Dr Marc Cartellieri
Career
present
Chief Scientific Officer at Cellex Patient Treatment GmbH
2013 - 2014
Post-Doc., Institute of Radiopharmaceutical Cancer Research Dep. Radioimmunology, Helmholtz Zentrum Dresden Rossendorf, Germany
2005 - 2013
Post-Doc., Institute of Immunology, TU Dresden, Germany
Education
2000 - 2005
Doctoral Thesis (PhD): “Untersuchungen zum Gag- und Pol-Protein des Prototypischen Foamyvirus (PFV)“, Institute of Virology, TU Dresden, Germany
1993 - 2000
Master of Science (Biology), Ernst-Moritz-Arndt-Universität Greifswald, Germany
Gareth Thomas
Dr Stephen Miller
Dr. Stephen Miller is the Judy E. Gugenheim Research Professor of Microbiology-Immunology at Northwestern University Feinberg School of Medicine in Chicago. He received his Ph.D. in 1975 from the Pennsylvania State University and did postdoctoral training at the University of Colorado Health Sciences Center before joining the faculty at Northwestern in 1981 where he currently serves as Director of the Northwestern University Interdepartmental Immunobiology Center. Dr. Miller is internationally recognized for his research on pathogenesis and regulation of autoimmune diseases. He has published over 360 journal articles, reviews and book chapters and has trained multiple generations of scientists. His work has significantly enhanced understanding of immune inflammatory processes underlying chronic autoimmune disease employing animal models of multiple sclerosis (MS) and Type 1 diabetes (T1D). His work has focused on the study of the cellular and molecular mechanisms underlying treatment of established T cell-mediated autoimmune diseases using antigen-specific immune tolerance. His current work is is geared to translating the use of antigen-linked biodegradable PLG nanoparticles for the treatment of human immune-mediated diseases including autoimmunity, allergy and tissue/organ transplantation.
Judy Gugenheim
Dr Giovanna Lombardi
Giovanna Lombardi is Professor of Human Transplant Immunology in the Division of Transplantation Immunology and Mucosal Biology, MRC Centre for Transplantation, at King’s College London (since 2005). From 1987 to 2005 she was based at the Department of Immunology at the Hammersmith Hospital and before that at the University of Rome, Italy.
Her research has focused on the mechanisms of transplant rejection and tolerance as well as on the phenotype and function of regulatory T cells (Tregs) in health and disease, both in the murine system and in man. Recently her laboratory has established a clinical protocol to expand Tregs in vitro. Tregs has been used in two clinical trials in renal transplant patients as part of a large EU cell therapy consortium and in liver transplant patients supported by the MRC. In parallel, her group has demonstrated that adoptive cell therapy using alloantigen-specific regulatory T cells can offer an advantage compared to polyclonal Tregs for preventing chronic allograft rejection. A GMP compatible cell sorter to generate highly pure Tregs is under validation and this approach will open the possibility of using alloantigen-specific Tregs for future clinical trials within the next few years.
Claudia Zylberberg, PhD
Professor Ulrike Koehl
Ulrike Köhl is a full professor and director of the Institute of Cellular Therapeutics at Medical School Hannover, Germany. Previously she worked at MD Anderson Cancer Centre in Houston, USA and at the University Hospital, Frankfurt, Germany. All her goals are focused on the development and manufacturing of cell-based therapies including Advanced Therapy Medicinal Products (ATMPs) and the improvement of cell processing strategies. She has a specific focus on primary human NK cells including chimeric antigen receptors (CAR) expressing NK cells. She is a member of numerous national and international societies and is serving as a reviewer for the European Medicine Agency.
Currently: Primo loco for a W3 professorship for immune oncology at the University Hospital Leipzig in personal union as the director of the Fraunhofer Institute of Cellular Therapeutics and Immunology in Leipzig.
Dr David Sourdive, PhD
David Sourdive, Ph.D., is a co-founder of Cellectis and joined the Board of Directors in 2000. Dr. Sourdive holds the position of Executive Vice President, Technical Operations, with the mission to develop the Company’s industrial and technological basis as well as to deploy its operations in the pharmaceutical arena. Dr. Sourdive combines a strong scientific expertise with experience in managing industrial programs bringing innovative technologies to industrial fruition. He served as Executive Vice President, Corporate Development, from 2008 to 2016. In addition to his role at Cellectis, Dr. Sourdive has also served on the board of directors of the Mediterranean Institute for Life Sciences. David Sourdive graduated from École Polytechnique, received his Ph.D. in molecular virology at Institut Pasteur and completed a research fellowship in the Emory University Department of Microbiology and Immunology. His management training is from the HEC (Challenge +) and his decade-long experience in industrial program management was acquired at the French Department of Defense (DGA) prior to Cellectis’ inception.
